Mamit is situated in the western part of Mizoram, roughly 95 kilometers west of the state capital, Aizawl. The town is enveloped by a dramatic landscape of steep hills, dense tropical forests, and winding river valleys. The broader district shares an international border with Bangladesh to the west, and state borders with Tripura and Assam to the north and northwest.
The geography is defined by a north-south alignment of hill ranges, which is characteristic of the Purvanchal Himalayas. The region surrounding the town is noted for its immense biodiversity, primarily protected within the nearby Dampa Tiger Reserve. The tropical evergreen and semi-evergreen forests are rich in bamboo, timber, and a wide variety of endemic flora and fauna.
The area is drained by several significant rivers, most notably the Tlawng, Tut, Teirei, and Langkaih rivers, which flow through the deep gorges between the hills, providing crucial water resources for agriculture and daily living.

