Given its status as a state capital and hill station, major corporate headquarters are rare, but it is home to important regional and state enterprises.
* **NEEPCO (North Eastern Electric Power Corporation):** A major public sector enterprise headquartered in Shillong, generating power for the region. * **Meghalaya Energy Corporation Limited (MeECL):** The state's primary power utility. * **Chillibreeze:** A notable local startup success, offering presentation design and corporate services to global Fortune 500 companies, while providing local employment. * **Tourism and Hospitality:** Numerous regional travel companies, boutique hotel chains, and eco-tourism ventures operate their head offices out of Shillong.